生殖道微生物与生殖健康

Reproductive tract microorganisms and reproductive health

摘要:

人类生殖道有多种微生物定殖，它们构成生殖道正常微生物菌群。乳酸杆菌是健康人群生殖道中最主要的微生物，具有维持生殖道生态平衡和防止病原体入侵的功能。微生态环境遭到破坏会导致各种感染，如细菌性阴道病、性传播感染、不良妊娠结局、不孕不育和肿瘤等。对生殖道炎症的治疗除常规的抗菌治疗外，益生菌在恢复菌群结构和维系生殖健康方面发挥着重要作用，本文就生殖道微生态与男女生殖健康相关性的最新进展进行综述。

Abstract:

A variety of microorganisms constitute the normal microbiota in human reproductive tract. Lactobacillus is predominant among the microorganisms in reproductive tract of healthy people as it maintains the ecological balance of reproductive tract and prevents the invasion of pathogens. Disruption of the micro-ecological environment can lead to various diseases such as bacterial vaginosis, sexually transmitted infection, adverse pregnancy outcome, infertility and tumor. In addition to conventional antimicrobial therapy, probiotics play an important role in restoring community structure and maintaining reproductive health in response to reproductive tract inflammation. This article reviewed the research progress on the correlation between reproductive tract microecology and reproductive health in men and women.