Abstract:Marine Microbiology Experiment, a core and basic course of marine science major in colleges and universities, plays an important role in the training of marine science talents. The ideological and political construction in Marine Microbiology Experiment course is very important for college education. This article introduces the overall thinking and practical exploration of "curriculum ideological and political education" in Marine Microbiology Experiment course from the following aspects:the mining and construction of curriculum contains ideological elements, teaching idea, teaching goal, teaching method, examination evaluation system, teaching reflection and so on. In such a way, ideological and political education was integrated into the teaching of Marine Microbiology Experiment course to realize synergy effect.