微生物角蛋白酶的特性及其应用研究进展

Research progress on the characteristics and application of microbial keratinase

摘要:

角蛋白作为家禽加工和农业废弃物的主要成分，因其结构中富含能抵抗普通蛋白酶和化学催化剂降解的稳定交联二硫键而难以被利用，因此每年都在环境中大量积累，造成了严重的环境污染。微生物角蛋白酶可将角蛋白废弃物转化为可再次利用的产物，带来了经济的可行性及环境的可持续发展。本文主要综述了角蛋白酶的生物化学特性、角蛋白酶的基本结构及其表达特性，总结了其应用价值及角蛋白降解机制，最后展望了微生物角蛋白酶的进一步研究方向。

Abstract:

Keratin is the main component of feathers and many agricultural waste. It is difficult to be used because it has a large number of stable cross-linked disulfide bonds, which can resist degradation of common proteases and chemical catalysts. These waste resources are accumulate massirely and cause serious environmental pollution. Microbial keratinase can efficiently convert keratin wastes into the reusable products which will bring economic value, and make environment sustainable. This article mainly reviews the biochemical characteristics, the basic structure, the expression characteristics, and the application of microbial keratinases. Finally, the future research topics of the microbial keratinase were proposed and prospected.