粘细菌资源挖掘与多相分类研究进展

Research progress in resources mining and polyphase classification of myxobacteria

摘要:

粘细菌（myxobacteria）是一类具有复杂多细胞行为、能够广泛捕食各类细菌和真菌并能产生丰富次级代谢产物的药源微生物，具有重要研究和应用价值。然而，由于资源挖掘困难，多相分类研究进展缓慢，严重阻碍了粘细菌的开发利用。本文对粘细菌的特性、分离和纯化方法、目前存在的不足及改进措施进行阐述，并对粘细菌多相分类研究进展及存在的问题进行解析。另外，结合当前技术手段和发展现状，进一步对粘细菌的未来发展趋势进行展望，以期为相关研究提供参考。

Abstract:

Myxobacteria are a kind of medical microorganisms that could produce abundant secondary metabolites, show complex multicellular behaviors and prey kinds of bacteria and fungi. Therefore, myxobacteria have important values of research and application. However, it seriously impedes myxobacterial mining and utilization because of their difficulties to isolate, cultivate, and research in polyphase classification. This review described myxobacterial features, methods for isolation and purification, and discussed existing problems and improvement measures. In addition, we also analyzed the research status in polyphase classification of myxobacteria. Based on the current technical means and research progress, the future research trends of myxobacteria were prospected. This review aims to provide help to relevant researches on myxobacteria in the future.