Abstract:Microorganisms are largely associated with food production, processing, storage, transportation and safety inspection and control. Microbiology is an important course that required by majors of Food Science and Engineering in most universities in China. We tried to reform teaching of Microbiology courses by adjusting the contents, strategies and performing a research-oriented teaching based on the training program of the Food Science and Engineering majors and the career development of graduated students in our college, in order to construct a rational teaching model of the course for those majors.