Abstract:Based on the needs of students of different majors in ethnic colleges/universities for knowledge of microbiology, this paper aims at reforming and practicing of Microbiology course teaching in the aspects of teaching content, teaching methods, teaching resources, etc. We have established a system of “four characteristics” microbiology teaching content, which combined systematization, pertinence, frontierness and effectiveness. Meanwhile, we have created a “three combination” microbiology teaching manner: theory and practice combination, in-class and out-of-class combination, and teaching and scientific research combination. Besides, a “student-centered” self-learning platform for microbiology has been built. These methods will strengthen the cultivation of students’ innovation ability, improve the quality of teaching.