Abstract:With the growing concern about the role of intestinal microbes in human health and disease, the metabolism of intestinal microorganisms has become one of the research hotspots in recent years. Previous studies have shown that applying intestinal microbiome and metabolomics may have important value in the host physiology, disease pathology, and pharmaceutical pharmacology. This paper reviews the research progress on the combined application of intestinal microbial genomics and metabolomics analysis.