Abstract:Reactive oxygen species (ROS) refers to a category of highly reactive substances formed by ground-state oxygen molecules acquiring electrons. ROS can be generated by aerobic respiration electron transport chain that helps maintain normal physiological activity of bacteria. Lots of exogenous ROS are generated and accumulated during cleaning and disinfection, medical treatment, etc. Excessive ROS would bring oxidative stress, lead to oxidative damage, and even affect activities of bacteria. In this review, we analyze the oxidative stress response induced by excessive ROS, the correlation between excessive ROS and the formation, recovery or repair of special non-spore status of bacteria, and even leading to their death, to provide reference for the innovation of effective control of spoilage and pathogenic bacteria.