Abstract:Ideological and political education is an important measure of the reform and innovation of the ideological and political courses in colleges and universities, which has gradually become the direction of the course reform because of its advantage of unity of moral and intellectual education. This study explored the effect of ideological and political education in Pathobiology and Medical Immunology for “5+3” integration of Traditional Chinese Medicine (TCM) program under the COVID-19 epidemic situation. The research subjects included two classes of “5+3” integration of TCM program in Grade 2018 in Chengdu University of TCM. We adopted traditional teaching mode in class 1 and teaching mode of ideological and political education in class 2. On the basis of traditional teaching mode, the ideological and political education materials were organically integrated into learning before, during and after the online lesson. At the end of the course, we conducted a survey about themes of patriotism, self-confidence in TCM, scientific literacy and mutual learning among civilizations to assess students’ understanding of the ideological and political elements between the two classes. At the same time, the students were also investigated for course satisfaction degree and the scores of ideological and political test, and the results were compared between the two classes. The score of ideological and political test and course satisfaction degree of class 2 were higher than class 1 (P<0.01), which indicated that the ideological and political education mode was better than traditional teaching methods under the COVID-19 epidemic situation. The ideological and political education mode was more effective in cultivating people with moral character while improving professional quality of medical students. Our study can provide a reference of ideological and political education for other medical programs, and promote the comprehensive advancement of ideological and political education in medical courses.