肠道内产丁酸细菌及其产物丁酸生理功能的研究进展

Butyrate-producing bacteria in the intestinal tract and the physiological function of their metabolite butyrate: a review

摘要:

产丁酸细菌是利用糖类发酵产生丁酸的一类细菌，代表种是丁酸梭菌。在动物及人类肠道内存在的产丁酸细菌主要是梭菌属、柔嫩梭菌属、罗斯式菌属、真菌属及丁酸弧菌属。本文一方面介绍部分肠道内产丁酸细菌的种类、特点及膳食纤维的摄入和肠道益生菌对产丁酸细菌的影响，另一方面对其主要代谢产物丁酸在体内的生理功能进行探讨，以期为产丁酸细菌的应用及产品开发提供理论依据。

Abstract:

Butyrate-producing bacteria is a kind of bacteria which produce butyrate by fermenting carbohydrate, and its representative species is Clostridium butyricum. The main genus of butyrate-producing bacteria in the intestinal tract of animals and humans are Clostridium, Clostridium leptum, Roseburia, Eubacterium and Butyrivibrio. On the one hand, this paper introduces the species and characteristics of some butyrate-producing bacteria, effects of dietary fiber intake and intestinal probiotics on butyrate-producing bacteria. On the other hand, the physiological function of its main metabolite butyrate in vivo was discussed. In order to provide a theoretical basis for the application and product development of butyrate-producing bacteria.