细菌产黄素类化合物介导的电子传递及对环境污染物的厌氧生物转化研究进展

Bacterial flavins-mediated electron transfer and its effects on anaerobic biotransformation of environmental pollutants: a review

摘要:

氧化还原介体能够加速有毒环境污染物的厌氧生物转化。黄素类化合物是一类微生物自身合成分泌的氧化还原介体，其应用可有效地避免外源性介体带来的成本较高及造成二次污染的问题，因此引起了广泛的关注。研究表明，细菌合成的微量黄素类化合物不仅能够作为黄素蛋白的辅酶因子参与偶氮染料、铬酸盐和硝基芳烃等污染物的厌氧生物转化，并且还可以分泌到胞外将电子传递给固态电子受体如含铁矿物和电极等来参与生物修复过程。根据黄素类化合物的功能，本文综述了黄素类化合物的合成与分泌，及其介导的胞内外电子传递和对环境污染物厌氧生物转化的影响，以促进其在实际环境污染物处理中的应用。

Abstract:

Redox mediators can accelerate anaerobic biotransformation of toxic environmental pollutants. Flavins are the redox mediators synthesized and secreted by bacteria. Their application can effectively avoid the problems of high cost and secondary pollution caused by exogenous mediators. Therefore, they have attracted wide attention. Many studies have shown that the trace amount of flavins synthesized by bacteria can not only be used as coenzyme factors of flavin proteins to participate in the anaerobic biotransformation of azo dyes, chromates and nitroaromatics, but also be secreted to extracellularly transfer electrons to solid electron acceptors such as iron minerals and electrodes for bioremediation. According to the functional roles of flavins, this paper reviews their synthesis and secretion, flavins mediated-intracellular and extracellular electron transfer, and their effects on anaerobic biotransformation of environmental pollutants, so as to promote their application in the treatment of environmental pollutants.