Abstract:Carrying out ideological and political education in Microbiology course was conducive to improving the ideological and moral cultivation and comprehensive quality of students of related majors. It was the specific requirement of the fundamental mission of fostering morality and cultivating talents in current college education, and an important embodiment of the routinization and normalization of ideological and political education. One of main teaching methods of ideological and political education in Microbiology course was to improve students’ ideological and moral level by guiding them to understand the ideological connotation of some famous scholars and their deeds in the development of microbiology. This method had achieved ideal teaching effect in practice. However, there were some drawbacks of this method, such as insufficient design and lack of fashionability. In view of these problems, this paper proposed a problem-based learning design of ideological and political education in Microbiology course based on the case about the outbreak of coronavirus disease 2019 (COVID-19). The design was intended to use some advanced deeds or bad phenomena which happened in the outbreak of COVID-19 by refining and relating them with knowledge of microbiology and classic case in the history to carry out the problem-based learning. The COVID-19 outbreak was an important event in students’ personal experiences. Therefore, using the COVID-19 case could greatly improve students’ sense of participation and arouse their resonance. It would be a beneficial supplement to classic case used in microbiology ideological and political education. It could lead students to explore the ideological and ethical significance of each case and internalize it into their own value belief while learning professional knowledge. It would be helpful for students in fostering correct world outlook, views on life and values. The design could be a good way to achieve the goal, combine ideological education with scientific knowledge learning, of ideological and political education in Microbiology course.