Abstract:Experimental teaching is an important part of undergraduate teaching of life sciences. This paper takes the course of Microbiology Experiment as the research object, using interactive website to conduct on-line and off-line blended teaching, evaluating students’ learning effects and rules, exploring the effect of blended teaching in experimental courses of life sciences, the possibility of popularization of the blended teaching mode is also be discussed. In three consecutive years of teaching practice, statistical analyzing of data from various dimensions shows that under blended teaching mode, the vast majority of students have the ability to study on their own initiative, at the same time, the depth and breadth of experimental courses have been improved. The monitoring and comprehensive evaluation of learning rules show that the students who study in-depth are outstanding in all kinds of evaluation indexes. Consequently, under the blended teaching mode, how to guide students to conduct real and effective depth learning is an important task for teachers using the new teaching mode.