“新工科”背景下“代谢工程”课程建设的思考

Reflections on the course construction of the Metabolic Engineering under the background of Emerging Engineering

摘要:

“代谢工程”是生物工程专业本科生与研究生的专业核心课程，无论是应对新兴产业的“智能制造”，还是针对传统发酵工业的升级改造，都能体现其“新工科”的特点。“代谢工程”更注重于培养学生综合运用专业知识来解决实践问题的能力，即合理进行代谢途径与调控网络的设计，实现目的产物的“生物智造”。基于“代谢工程”综合性、时效性、应用性都很强的特点，我们通过明确课程定位、注重经典内容、紧跟学科发展、突出实际应用、强调师生互动等教学方式，不断优化教学体系和教学内容，提出了注重衔接、案例启发、前沿展示、归纳总结等多种教学思路，在教学过程中有效地激发了学生学习兴趣，增强了学生的学习效果，为高层次“新工科”创新人才培养奠定了基础。

Abstract:

Metabolic Engineering is a core course for undergraduate and graduate students major in Bioengineering. Whether it is “intelligent manufacturing” for emerging industries or the upgrade of traditional fermentation industry, this course can reflect the characteristics of the Emerging Engineering. Metabolic Engineering is more focused on cultivating students’ ability to comprehensively use professional knowledges to solve practical problems, that is, to rationally design metabolic pathways and regulatory networks to achieve the “bio-intelligent manufacturing” of the target products. Based on the comprehensive, time-effective, and applied characteristics of Metabolic Engineering, we have clearly defined the course goals, focused on classic content, followed the discipline development, highlighted practical application, and emphasized teacher-student interaction to continuously optimize the teaching system and teaching content. In this course, we also put forward a variety of teaching ideas such as “laying stress on the succession of teaching contents”, “inspiring students’ thinking through typical cases”, “displaying cutting-edge developments of the discipline”, and “summarizing the important teaching contents”. In the teaching process, this course has effectively stimulated students’ interests in learning, enhanced their learning effects, and layed a solid foundation for the cultivation of high-level Emerging Engineering innovative talents.