Abstract:This project intends to adopt the presentation-assimilation-discussion (PAD) teaching method to carry out teaching reform exploration and practice in Food Microbiology, aiming to analyze the applicability of this method to Food Quality and Safety major courses in Medical universities. The results show that using PAD method in course of Food Microbiology improved the students’ enthusiasm for learning, capacity to think and explore, and skill to communicate. At the same time, it trained teachers’ organization ability, speech and evaluation skills. In addition, it improved the relationships between students and teachers and the relationships between students and students. The PAD method is simple and efficient for improving teaching quality.