真菌小RNA的发生及其作用机制

Research advance on the generation and mechanism of small RNAs in fungi

摘要:

小RNA是真核生物体内一种含量丰富的内源性非编码RNA，通过与其靶mRNA完全或非完全互补结合调控真核生物的基因表达。本文全面综述了真菌中已发现的小RNA种类、小RNA发生相关蛋白因子以及小RNA的具体作用机制，为进一步研究小RNA对真菌生长发育的调控机制提供重要参考。

Abstract:

Small RNAs are small, endogenous and non-coding RNAs and rich in eukaryotes, they regulate the gene expression through complete or non-complete complementary with the mRNA. In this review, we summarized the discovered classes of fungal small RNAs, protein factors biogenesis related with small RNAs, and provide a current analysis of the small RNAs mechanisms. This will provide the important reference for the scientists to further study the mechanisms of fungal small RNAs in growth and development.