Abstract:Fermentation Engineering is one of the core course of Biotechnology and Bioengineering major, being characteristics of practice. The process of fermentation involves in the strain and culture medium, the bacterial seed preparation, fermentation kinetics, process control, production, separation and refining of fermentation products. During the actual production process, each step depends on the specific fermentation theory. If only the basic theory of textbooks is presented, without combining with production practice in the course, the students not only have difficulty in study, but also have no deep understanding of the fermentation process of products. Moreover, they do not know how to combine the theoretical knowledge with the actual production. Thus, the teaching method of Fermentation Engineering course based on the guidance of practice can stimulate the learning interest of the students. Meantime, it can strengthen their understanding of theoretical knowledge. More importantly, the methods used to solve the problems in the actual production process, have important application value to the students in their scientific researches.