Abstract:In recent years, the discovery of heterotrophic nitrification-aerobic denitrification bacteria has broken the traditional theory. It is not only able to simultaneously remove nitrogen and organics, but also some bacteria can achieve simultaneous nitrification and denitrification (SND), so it has gained widespread attention. Our review focuses on the influence factors of heterotrophic nitrification-aerobic denitrification bacteria, the optimal nitrogen removal effect of some bacteria, the difference between traditional nitrification-denitrification bacteria and heterotrophic nitrification-aerobic denitrification bacteria and the nitrogen metabolic pathways of some bacteria. In addition, it shows the research progress in the aspects of NO2?-N control and compound bacteria. Finally, the present situation of its application in bioaugmentation and challenges facing it are brought forward.