Abstract:Rumen methanogens can generate CH4 using hydrogen, methanol, methylamine and other substances. CH4 emissions from ruminants not only cause the dietary gross energy loss, but also have a negative effect on environment. Therefore, many scholars are looking for methods to reduce methane emissions from ruminants. Among the strategies, the use of Direct-fed microbes (DFM) is one possible option to decrease rumen CH4 emission, which remains in the phase of initial exploration. We review several vital DFMs and the mode of action that can be modulated by the use of DFM, and study on the use of DFM for mitigation of ruminant CH4 emissions.