Abstract:As a novel nanomaterial, fluorescent quantum dots (QDs) have been synthesized by a variety of approaches, including physical, chemical and biological (bionic) methods. Among these methods, biosynthetical technique has gained increasing interest for its environmentally friendly process and good biocompatibility of product. Based on the literatures, this review summarized the methods to manufacture fluorescent QDs by different biomatrices, such as bacteria, fungi, some other living organisms, and bionic. We also addressed the prospects of biosynthetical (bionic) methods.