Abstract:For the purpose to increase interests in knowledge learning, operation techniques training, innovative thinking developing, and quality education promoting for collage students, a three-in-one training system were developed and practiced. The system includes lectures in class, experiment in laboratory, and subject research training with the scientific project. And some reformation on teaching method and assessment systems were also included. Among this, a three-way interaction training, that is, teachers, graduate students, and undergraduates, was the key step of the program. And this is the first time that graduates were introduced to quality education of undergraduate. The results indicated that these systems were effective on skills training, learning interest stimulating, innovative thinking development for undergraduates, and enhance the quality-oriented education both for undergraduates and graduates. The system was an effective and useful method for microorganism education.