Abstract:In order to improve students’ ability of autonomous learning and cooperative learning, we adopted the teaching model of autonomous and cooperative learning in a team based on task driven in Microbiology teaching. In the model, the main line was task, in which the teaching contents and ability objectives were implied, and the teacher was a leader, who guided the students (the main body) to make use of learning resources, construct knowledge and improve ability through individual autonomous learning and team cooperative learning. Three rounds of teaching practice showed that the pattern stimulated the students’ leaning enthusiasm, cultivated students’ comprehensive ability and innovation consciousness. What’s more, the pattern promoted the teacher’ teaching level.