Abstract:Gut microbes are associated with the human health directly. Up till now, scientists have conducted many researches on the impact factors of gut microbiota structure both in human and animal models (i.e. mice and pigs), and got many achievements. In this paper, we focused on the impact factors of human’s gut microbiota structure, including the age, the host genotype, the postnatal environment, diet, antibiotic and so on. By recognizing and controlling these factors can help human keeping a healthy life.