Abstract:Gosling plague is one of the most common diseases with high mortality in gosling, which could induce huge economic losses and cause serious damage to the development of goose industry. In order to improve the level of scientific understanding, disease prevention and control on gosling plague, the peers performed a lot researches, with the long-term perseverance in our country and obtained a series groundbreaking achievements. Gosling plague and its pathogen goose parvovirus (GPV) were first discovered and identified by Dingyi Fang in the world. The variation characteristics of the genetic evolution of GPV were analyzed and the distribution area and epidemiology situation of the Gosling plague in China were investigated preliminarily. As well, on the basis of traditional testing methods, together with the modern immunology and molecular biology technique, a series of rapid diagnostic methods were established. Furthermore the high titer serum, attenuated vaccines for goslings and adult geese were successfully developed to effective controlling of this disease. And some cell-adapted GPV strains were successfully obtained and further applied in clinic, which provided a new vaccine candidate for gosling plague control. All the achievements and progress above lay a good foundation for the gosling plague prevention and control.
