胃肠道微生物及其分子生态学技术研究进展

Molecular ecology applied to gastrointestinal tract microorganisms

摘要:

由于与人类健康和疾病密切相关，胃肠道微生物研究已成为当今的热点研究领域。目前研究的分子手段已经从单纯的分析微生物群落结构组成，发展到通过宏转录组学、宏蛋白组学和代谢组学等“组学”技术揭示胃肠道微生物群落的相应功能。本文结合我们的研究工作，综述了国内外胃肠道微生物及其分子生态学技术的研究进展。

Abstract:

For health and disease, the gut microbial community of humans has received significant attention from researchers. The application of 16S rRNA-based molecular technology enables researchers to study the microbial composition in the gut ecosystem. Developments in “omics” approaches have made it possible to reveal the function of microbes in the gastrointestinal tract. In this paper, combined with our own findings, we summarized advances in molecular ecology applied to studying gastrointestinal tract microorganism.