钙粘蛋白与苏云金芽胞杆菌晶体毒素 互作机制研究进展

Progress on the mechanism of interaction of cadherin with crystal toxin of Bacillus thuringiensis

摘要:

昆虫钙粘蛋白是苏云金芽胞杆菌晶体毒素的重要受体之一, 本文简述了昆虫钙粘蛋白种类、结构特征和在昆虫体内的分布, 对昆虫钙粘蛋白与苏云金芽胞杆菌毒素相互结合位点进行了较深入讨论; 详细论述了苏云金芽胞杆菌晶体毒素作用孔洞模式和信号转导模式, 并简要介绍了钙粘蛋白与昆虫抗性的关系。

Abstract:

Cadherin is one of the most important receptors for crystal toxins of Bacillus thuringiensis in insects. The type, structure and distribution of cadherin in insects are sketched. The binding sites of both crystal toxin and cadherin are discussed in depth. The mechanism of interaction of cadherin with crystal toxin of Bacillus thuringiensis is expounded in detail, and the relations betweeen cadherin and insect resisitance are also presented.