Abstract:To establish the experimental evaluation system taken the experiment process management as the foundation, the reasonable evaluation index as the core, and the evaluation of students’ comprehensive experimental ability as the goal, with the implementation of the reform of medical microbiology disciplines experimental teaching. To construct a reasonable evaluation index, to evaluate students’ basic technical ability, scientific experimental thought, and comprehensive exploring ability scientifically at different levels. To issue questionnaires and to interview with students in order to find out whether the reform is successful. As can be seen from the questionnaires and interviews, the reform of evaluation system turned out to be successful. The new experimental evaluation system can reflect students’ experimental and comprehensive abilities with the incomparable superiority to the traditional one.