Abstract:Focusing on the training on the graduate students’ academic and innovating ability, a reforming practice on teaching model in the course Metabolic Engineering was discussed. Firstly, the course contents renewing was conducted via a PPT renewing on line and real time in the class. Secondly, a class teaching model, lectures on core contents by teachers plus a series of seminars simulating international conference by students, was constructed. Finally, a comprehensive test method, exam on theory plus evaluation of student’s comprehensive ability, was implemented. All the above practices are helpful to enhance academic and innovating ability of the graduate students.