Pathogens is a major cause of gastrointestinal illness and hazardous to human health. Application of probiotics to the prevention of pathogen infection has received much attention due to safety and decreasing drugtolerance. Here we summarize the recent progress in mechanism of probiotic bacteria inhibition of pathogens including competition for adhesion sites with pathogens, coaggregation with pathogens and production of antimicrobial substances.
