Food spoilage caused by the bacterial biofilm is a signi?cant problems in food industry. It is indicated that quorum sensing of the bacteria plays a major role in bio?lm formation and food spoilage. This review focuses on the recent research advances about various quorum-sensing signaling molecules produced by bacteria, the role of signaling molecules in bio?lm formation and the signi?cance of bio?lms in food industry. As quorum-sensing signaling molecules are closely relate to food spoilage, it was also reviewed that quorum-sensing inhibitors can be developed to be used as novel food preservatives for enhance shelf life and food safety.
