马铃薯Y病毒属病毒P3和P3-PiPo蛋白功能研究进展

The functional characterization of Potyvirus-encoded P3 and P3-PiPo protein

摘要:

Potyvirus属于马铃薯Y病毒科Potyviridae, 是最大的植物病毒属, 给农业生产造成严重的经济损失。P3是Potyvirus属病毒中变异很大、功能较复杂的编码蛋白, 涉及到病毒复制、侵染、抗性及细胞间运动; P3-PiPo是P3编码框内新近发现的Potyvirus重要编码蛋白, 已证实它在病毒的细胞间运动中起着决定性的作用。对病毒蛋白功能的研究为该属病毒的研究发展提供重要的理论基础, 对Potyvirus侵染机制及抗病机理研究具有指导价值。

Abstract:

Potyvirus belonging to family Potyviridae, is the largest plant virus family, which can be responsible for severe economic losses to agriculture world-wide. P3 protein of potyviruses show relatively low homology in compared to other proteins among potyviruses and multi-functional, related with virus replication, infection, resistance and cell-to-cell movement. P3-PiPo, the newly found SMV-encoded protein, is an overlap protein produced via ribosomal frameshifting or transcriptional slippage at a highly conserved within the P3 cistron and play a key role in viral cell-to-cell movement. The functional characterization of potyvirus-encoded proteins supported the understanding of potyviruses, and promoted the research of potyviruses infectious and resistant mechanisms.