水稻黄单胞菌三型分泌系统效应物的研究进展

Current progresses in study on T3SS effectors of Xanthomonas oryzae

摘要:

水稻黄单胞菌(X. oryzae)三型分泌系统(Type Ⅲ secretion system, T3SS)效应物(Effector)一直被认为是水稻黄单胞菌最重要的致病因子之一。水稻黄单胞菌水稻致病变种(Xanthomonas oryzae pv. oryzae)和水稻黄单胞菌栖稻致病变种(Xanthomonas oryzae pv. oryzicola)分别引起水稻两大细菌病害水稻白叶枯病(Bacterial leaf blight)和水稻细菌性条斑病(Bacterial leaf streak)。基因组分析揭示, 水稻黄单胞菌中至少存在28个家族的T3SS效应物, 分为TAL (Transcription activator-like effectors)效应物和non-TAL效应物(Non transcription activator-like effectors)两大类。通过对水稻黄单胞菌中T3SS效应物的数量、种类、结构、宿主靶标等方面进行综述, 为全面了解水稻-水稻黄单胞菌互作的分子机理, 调控网络以及水稻分子育种提供一种新洞察力。

Abstract:

The type Ⅲ secretion system (T3SS) effector is considered as one of the key virulence factors in Xanthomonas oryzae. X. oryzae pv. oryzae and X. oryzae pv. oryzicola cause bacterial leaf blight and bacterial leaf streak in rice, which are important bacterial diseases of rice. Based on bioinformatic analysis of the bacterial genome and other recent reports, X. oryzae contains at least 28 classes of T3SS effectors, divided into two groups: TAL (transcription activator-like) effectors and non-TAL (non tran-scription activator-like) effectors. This paper reviews the number, classes, structure and host targets of T3SS effectors in X. oryzae, which may provide a new insight into the mechanism of rice-X. oryzae in-teraction, regulatory network and molecular breeding of rice.