宏基因组学技术的研究与挑战

The research innovation and challenges in metagenomics

摘要:

宏基因组学研究作为研究微生物种群生态分布、群体遗传特征和基因相互作用的新兴学科领域, 在很大程度上促进了环境微生物资源, 特别是未培养微生物资源的开发利用, 在土壤、海洋、人体医学、药物等各个领域的应用中取得了突破性的进展, 为发现新的生物活性物质提供了新的有效途径。就宏基因组学研究进展进行综述, 并重点介绍了宏基因组学研究中的机遇及挑战。

Abstract:

As the new scientific field of studying the gene function and interactions of microbial community, metagenomics has largely contributed to the development and utilization of microbial resources, and made breakthrough progress in various fields, such as soil, oceans, human medical, pharmaceutical and so on. Metagenomics provided a novel approach for the discovery of new bioactive substances. Here we discuss some recent progress with emphasis on the opportunities and challenges in metagenomics applications.