Abstract:Fermentation engineering is a very important specialized course for undergraduates majoring in biological engineering specialty, and its teaching quality will affect students’ professional quality, in recent years, the course reform has been conducted. For the arrangements of teaching content system, the concept of “One center, Two combination, Three levels” was put forward. About the teaching strate-gies, the comprehensive application of four strategies which involved “Predicting, Questioning, Clari-fying and Summarizing” was explored. In the way of teaching medium, a variety of methods and tech-niques were attempted. In the process of practical teaching, new experimental weeks and the form of experimental groups were adopted, and the teaching evaluation system was perfected, meanwhile, at-taching importance to students’ innovative ability and professional skill to improve teaching quality.