链霉菌调控蛋白DasRABC的研究进展

Study of DasRABC in Streptomyces

摘要:

越来越多的研究证明DasR及其相邻的DasABC转运蛋白超家族在链霉菌代谢和形态分化中发挥重要调控作用。就DasR的结构、调控序列特点及其与DasABC的关系、DasRABC调控链霉菌发育及次生代谢、DasRABC与链霉菌营养利用等几方面讨论调控蛋白DasRABC的研究进展。

Abstract:

DasR and adjacent DasABC transporter play an important role in both metabolism and morphological differentiation of Streptomyces. In this article we review current understanding of DasRABC in Streptomyces as the followings: structure, regulatory sequence features of DasR and its relationship with DasABC; Function of DasRABC in development and the secondary metabolites of Streptomyces; DasRABC for the uptake of nutrient in Streptomyces.