Abstract:A reformation probe of bio-pharmacy major of higher vocational education has been practiced on background of the development of the higher vocational education theories and the bio-pharmaceutical industries. We analyzed the nessecities, bases, theories and characters of this reformation. And we also discussed the items, content, effects and prospects of this reformation. We established education model on the basis of cooperation of the college and the enterprises, and the tie of employment and learning. We reformed the curricula and the teaching content. And we established a practical education system with the core of practical training center of inside and outside the campus.