蛋白磷酸酶抑制剂变构霉素的生物合成及其抑制位点研究

Biosynthesis of Tautomycin and Its Inhibition Region of Protein Phosphatase

摘要:

变构霉素具有很强的蛋白磷酸酶抑制作用和良好的抗菌活性, 尤其是对油菜菌核病的抑制作用。本文综述了近年来有关变构霉素生物合成和蛋白磷酸酶抑制位点方面的最新研究进展。

关键词:蛋白磷酸酶, 变构霉素, 生物合成, 抑制

Abstract:

Tautomycin is one of well-known specific protein phosphatase inhibitors and exhibiting potent antifungal ability, especially to Sclerotinia sclerotiolum. This article reviews the recent research progress of tautomycin, focusing on its inhibition region and biosynthesis.

Key words:Protein phosphatase, Tautomycin, Biosynthesis, Inhibition