一株来源于海洋的抗肿瘤放线菌的分离鉴定

Isolation and Identification on One Marine Actinomycete Strain with Antitumor Activity

摘要:

从福建东海海滩土样品中分离到一株海洋放线菌FIM02-523, 该菌株的发酵产物具有抗肿瘤活性。菌株FIM02-523在多数培养基上生长良好, 橙色-暗棕色, 无气生菌丝, 不产生可溶性色素。系统发育、化学分类特征、形态特征、生理生化特性等分析表明菌株FIM02-523是小单孢菌属(Micromonospora), 可能是模式菌种青铜小单孢菌(Micromonospora chalcea)的一个菌株。

Abstract:

One marine actinomycete strain FIM02-523 was isolated from marine soil in the East China Sea in Fujian Province. The fermentation broth of strain FIM02-523 exhibited potent antitumor activities. Strain FIM02-523 grew well on most media tested, the colonies were orange to dark brown but lacked aerial hyphae, no diffusible pigments were observed. Phylogenetic, chemotaxonomic, morphological analyses, physiological and biochemical characteristics demonstrated that strain FIM02-523 belong to the genus Micromonospora, may be a strain of the type species Micromonospora chalcea.