“Microbiological Examination” is an important core course for medical examination technology major with a strong attribute of practicality and operability. A method of “Cooperation between school and hospital” is employed in the teaching of the course. It is based on the standards for medical professional education required by the hospitals, coupled with our teaching program. In the course of teaching, emphasis is laid on the philosophy of work-learn combination, using methods such as the analysis of individual cases to broaden students’ thinking and develop a sound scientific attitude. By way of “training-on-job learning-interning”, we can cultivate students’ ability of working with their own hands, as well as that for analyzing and solving problems. In this way, our school will be able to provide “talents with medical examination skill that can be put to practical use” for clinical application.