戈登链球菌的生物学特性及在黏膜疫苗的应用

The Bionomics of Streptococcus gordonii and Its Application in Mucosa Vaccine

摘要:

戈登氏链球菌是一种非致病性革兰氏阳性黏膜共生菌, 参与组成人类口腔正常菌群。它具有特殊的生物学特性, 非常适合作为黏膜疫苗的载体。了解戈登氏链球菌的生物学特性, 常用表达体系及该菌在黏膜疫苗的应用情况, 将为其黏膜疫苗的进一步研制提供重要参考。

关键词:戈登氏链球菌, 黏膜疫苗, 疫苗载体

Abstract:

Streptococcus gordonii is a nonpathogenic gram-positive commensal bacterium and component of the normal microbial flora of the human oral cavity. It is suitable to be as a mucosa vaccine vector due to its special bionomics. knowing the bionomics of Streptococcus gordonii , the general expressing system , and the application of it in mucosa vaccine, will provid important reference for the further development of its mucosa vaccine.

Key words:Streptococcus gordonii, Mucosa vaccine, Vaccine vector