Abstract:The mass utilization of chemical fertilizer not only is a problem of environment, but also an energy issue. To inoculate beneficial microorganisms has been the topic of scientist to cope with it. The bacteria achieve the goal through the way of dissolving nutrients unavailable, restraining pathogeny, reducing deleterious compounds and so on. However, it should be colonized in soil first to realize its function. This paper summarized factors, both in biologic and abiological aspects that affected successful colonization and activity of bacterial inoculation. The impacts of inoculated bacteria on population structure of specific rhizobacterial communities and environment should also be paid an eye on.