Abstract:The undergraduates majoring in biological sciences (teacher training) possess both specialized and systematic microbiological knowledge and the dual identity of current students and future teachers. In view of the needs for enhancing microbial literacy in the society, we practiced project-based teaching of Microbiology with microbial science activities as a carrier. The results showed that this new teaching approach improved the knowledge understanding of students, teaching performance, personal value shaping, and social responsibility implementation. Moreover, the results of this project can provide new ideas for science popularization in the public.