Abstract:The rapid advancement of microbiol technology is driving progress in medicine, agriculture, and industry, while simultaneously giving rise to increasingly severe and complex ethical challenges. This paper selects three representative crisis cases—the bacterial warfare by Unit 731, fecal microbiota transplantation (FMT), and mirror life research—as core analytical specimens to systematically diagnose multi-dimensional ethical pathologies embedded in these cases, including the alienation of scientific research ethics, crises of data privacy, dilemmas of distributive justice, and risks to civilization continuity. On the basis of this diagnosis, the paper constructs a comprehensive instructional intervention framework. This framework encompasses the restructuring of curriculum modules to integrate scientific knowledge and ethics dimensions, the introduction of immersive teaching methods such as case seminars and role-playing simulations, and the reform of assessment systems towards competency-oriented evaluation. This systematic protocol aims to organically incorporate the full-chain ethics education—foundation in ethical theory, cultivation of moral consciousness, internalization of ethical norm, and forging of ethical judgment—into the entire process of Microbiology teaching. The ultimate goal is to cultivate a new generation of high-quality microbiology talents who are courageous in ethical responsibility, proficient in scientific exploration, and adept at innovation leadership.