Abstract:Food Microbiology is a fundamental course for food science and engineering, food quality and safety, brewing engineering and other food science-related majors, holding a core position in the talent cultivation system. Under the educational concept of ideological and political education in courses and the development of emerging engineering education, our teaching team has focused on the problems, such as ignorance of quality goals and ability goals, poor implementation of all-round, all-process and all-staff education, and insufficient attention to the student-centered teaching, existing in conventional classroom teaching. We actively explored the path of teaching reform and constructed a new model of classroom teaching reform of “one-one-three-four” guided by the concept of outcome-based education. Specifically, “one course objective” focuses on cultivating high-quality food talents with solid theoretical knowledge, excellent practical ability, and outstanding comprehensive quality. “One spiritual guidance” integrates the craftsmanship spirit of Lu Ban and Mozi into the entire teaching process to foster students’ values and professional literacy. “Three reform strategies” refer to flipped classrooms for precise diagnosis of students’ knowledge mastery, team collaboration for enhancing comprehensive capabilities, and task-driven experiments for increasing learning challenges, which are coupled with the integration of ideological and political elements into teaching to promote the all-round development of students’ knowledge, abilities, and literacy. “Four dimensions of teaching evaluation” encompass knowledge, practice, engineering competence, and comprehensive quality, and a combined method of quantitative and qualitative assessment is adopted to scientifically evaluate students’ learning effectiveness and development potential. Practice has demonstrated that this model remarkably enhances students’ capabilities in knowledge application, engineering practice, innovation awareness, and craftsmanship spirit, thereby providing a replicable and scalable new paradigm for the teaching reform of food science-related courses.