Abstract:By analysis of the “man-oriented” viewpoint, the paper revealed that teach students in accordance of their aptitude and advancing in proper sequence were the specific expressions and implementations in higher education. Expounding the concrete methods and measures from “teaching” and “learning” two aspects combined with Microbiology teaching practice, that classroom teaching is basically students centered, the teacher should carry out the forms of school running, course contents based on the needs of students and their ability to learn, and it is important for college students study that teacher must play the guiding role in learning, because of classroom learning must be combined with experimental learning practice and knowledge should be advanced by steps and making steady progress, which further shows that comprehensively carry out the education principle of the “man-oriented” is special importance or significance to microbiology teaching in higher education.