整联蛋白与口蹄疫病毒感染

Integrin and Foot-and-mouth Disease Virus Infection

摘要:

整联蛋白是一类分布广泛的细胞表面受体家族， 它不仅在细胞的生长、移行、增殖和分化等许多方面发挥重要生物学功能，而且在多种病理过程中发挥重要作用。许多病毒都能利用整联蛋白分子作为病毒受体或共受体进入宿主细胞。本文主要就整联蛋白的特征及其在口蹄疫病毒感染宿主细胞过程中的作用机制进行综述。

Abstract:

Integrins are a family of cell surface glycoproteins that contribute to a variety of biological functions, including cell growth, migration, proliferation and morphology. In addition, integrins also play the important roles in pathological process. Several viruses have been showed to use integrins as receptors or co-receptors to infect host cells.This article mainly reviews the progress on integrins and their roles in FMDV infection.