元蛋白质组分析——研究微生物生态功能的新途径

Metaproteome——a New Approach for Studying Microbial Ecology Functions

摘要:

随着对微生物纯化培养和元基因组学研究的不断深入，积累了大量的微生物基因组信息，元蛋白组分析将促进我们对基因组功能的理解。目前，对微生物群落的元蛋白质组(metaproteome)的研究已成为后基因组时代进一步认识微生物生态功能的有效途径。对这一新技术的介绍结合元蛋白质组的提取和鉴定方法、元蛋白质组在研究微生物生态功能上的应用进行了综述，并对这一新的研究领域所面临的困难与挑战进行了讨论。

Abstract:

The information of microbial genomics is accumulated with the progress of pure culture and metagenome research. Metaproteomic study will contribute to our understanding of genomic function. Recently, metaproteomic study of microbial community is becoming an effective approach to understand the function of microbial ecology in post-genome era. In this review, the new metaproteomic approach was introduced, including extraction and identification of metaproteomes and application in microbial ecology. Finally, the future perspectives were discussed.