In order to make students have integrative qualities and reform the shortage of former teaching methods in the food microbiology experiment, a new experiment teaching system was established, introducina the integrative and innovative experiment to the students gradually. The reformation of experiment in food microbiology has trained the students well and improved their special skills. Most important of all, it can offer them a chance to realize their own ideas. The students can design an innovative and integrative experiment to carry out their originalities. Good effects have been made since this system is very helpful to improve their consciousness of innovation and integrative abilities in doing experiments.