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2025年3月29日 周六
首页 > 过刊浏览>2025年第52卷第3期 >896-904. DOI:10.13344/j.microbiol.china.240480
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我国畜禽细菌类主要兽医病原微生物及其疫苗研制与应用概况
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国家重点研发计划(2022YFD1800903,2022YFD1800703)；兽药行业公益性重点专项(GY202403)


Overview of bacterial pathogens and vaccines in livestock and poultry industry in China
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    摘要:

    我国畜禽养殖体系庞大，细菌类病原微生物在畜禽间流行传播引发的畜禽疫病频发不仅会造成严重的经济损失，部分病原菌还会引发人兽共患病，威胁公共卫生安全。本文对我国近年来流行的家畜和家禽细菌类病原微生物进行了概述，并梳理了目前我国家畜和家禽疫苗研制和应用情况，以期为我国细菌类畜禽疫病的防控提供理论基础。

    Abstract:

    China has a large livestock and poultry industry. The frequent occurrence of diseases caused by the spread of bacterial pathogens not only cause serious economic losses of this industry but also threaten public health and safety since some pathogens can cause zoonoses. This article provides an overview of the prevalent bacterial pathogens attacking the livestock and poultry industry in China in recent years and summarizes the current development and application of vaccines for domesticated animals in China. This review is expected to provide a theoretical basis for the prevention and control of bacterial diseases attacking the livestock and poultry industry in China.

    参考文献
    [1] 丁家波. 新时代背景下的兽医微生物学发展[J]. 微生物学通报, 2022, 49(12): 4961-4963. DING JB. Veterinary Microbiology development in the context of the new era[J]. Microbiology China, 2022, 49(12): 4961-4963(in Chinese).
    [2] 常帅, 刘嘉, 叶静, 陈焕春, 曹胜波. 新发展理念视阈下的我国畜禽疫病防控[J]. 中国科学院院刊, 2019, 34(2): 145-151. CHANG S, LIU J, YE J, CHEN HC, CAO SB. Study on prevention and control of animal infectious diseases in China from perspective of new development vision[J]. Bulletin of Chinese Academy of Sciences, 2019, 34(2): 145-151(in Chinese).
    [3] 张文婷, 汪琛, 张腾飞, 商雨, 王红琳, 卢琴, 罗玲, 罗青平, 邵华斌. 无抗养殖趋势下的家禽细菌病防控[J]. 中国家禽, 2019, 41(22): 1-4. ZHANG WT, WANG C, ZHANG TF, SHANG Y, WANG HL, LU Q, LUO L, LUO QP, SHAO HB. Prevention and control of poultry bacteriological diseases under the trend of antibiotic-free breeding[J]. China Poultry, 2019, 41(22): 1-4(in Chinese).
    [4] GŁOWACKA P, ŻAKOWSKA D, NAYLOR K, NIEMCEWICZ M, BIELAWSKA-DRÓZD A. Brucella- virulence factors, pathogenesis and treatment[J]. Polish Journal of Microbiology, 2018, 67(2): 151-161.
    [5] 文志, 韩艳秋, 王俊瑞. 布鲁氏菌毒力因子研究进展[J]. 微生物学通报, 2021, 48(3): 842-848. WEN Z, HAN YQ, WANG JR. Virulence factors of Brucella: a review[J]. Microbiology China, 2021, 48(3): 842-848(in Chinese).
    [6] 沈志浩, 朱新文. 布鲁氏杆菌病的防治和诊断[J]. 畜牧兽医杂志, 2023, 42(6): 141-143. SHEN ZH, ZHU XW. Prevention and diagnosis of brucellosis[J]. Journal of Animal Science and Veterinary Medicine, 2023, 42(6): 141-143(in Chinese).
    [7] 中华人民共和国农业农村部公告(第573号)[EB]. 中华人民共和国农业农村部公报, 2022(8): 118-120. Announcement No. 573 of the ministry of agriculture and rural affairs of the People’s republic of China[EB]. Gazette of the Ministry of Agriculture and Rural Affairs of the People’s Republic of China, 2022(8): 118-120(in Chinese).
    [8] 樊晓旭, 张皓博, 付树芳, 刘蒙达, 亓菲, 苏华彬, 李桂梅, 南文龙, 孙淑芳, 范伟兴. 全球人兽共患结核病防控现状与展望[J]. 中国人兽共患病学报, 2023, 39(5): 487-491. FAN XX, ZHANG HB, FU SF, LIU MD, QI F, SU HB, LI GM, NAN WL, SUN SF, FAN WX. Global status and prospects of zoonotic tuberculosis control[J]. Chinese Journal of Zoonoses, 2023, 39(5): 487-491(in Chinese).
    [9] 杨鲁琦, 沈鸣逸, 沙巍, 陈颖盈, 王颖. 卡介苗的免疫保护机制及其改造策略进展[J]. 中国防痨杂志, 2020, 42(8): 863-868. YANG LQ, SHEN MY, SHA W, CHEN YY, WANG Y. Research progress in immunoprotective mechanism of bacille Calmette-Guérin and vaccine development strategies[J]. Chinese Journal of Antituberculosis, 2020, 42(8): 863-868(in Chinese).
    [10] 佟仁冬, 冯妍, 刘燕, 张一帜, 任小侠, 郝力力, 朱良全, 姚文生. 分光光度法快速测定副鸡禽杆菌菌液浓度的应用[J]. 微生物学通报, 2024, 51(7): 2702-2710. TONG RD, FENG Y, LIU Y, ZHANG YZ, REN XX, HAO LL, ZHU LQ, YAO WS. Spectrophotometry for rapid determination of the concentration of Avibacterium paragallinarum[J]. Microbiology China, 2024, 51(7): 2702-2710(in Chinese).
    [11] 康翠翠, 陈小娇, 张妹, 陈文平. 鸡传染性鼻炎的流行情况及诊断要点[J]. 山东畜牧兽医, 2023, 44(7): 33-35. KANG CC, CHEN XJ, ZHANG M, CHEN WP. Epidemic situation and diagnostic points of infectious rhinitis in chickens[J]. Shangdong Journal of Animal Science and Veterinary, 2023, 44(7): 33-35(in Chinese).
    [12] 陈尧贵, 张熠, 贾胜军, 程振涛. 鸡沙门氏菌病研究进展[J]. 中国畜禽种业, 2023, 19(9): 136-142. CHEN YG, ZHANG Y, JIA SJ, CHENG ZT. Research progress of Salmonella in chickens[J]. The Chinese Livestock and Poultry Breeding, 2023, 19(9): 136-142(in Chinese).
    [13] 林志敏, 林彬彬, 谢碧林, 徐以娟, 林锋强, 闫露, 李翠婷, 周海欧, 李兆龙. 鸭疫里默氏杆菌PT-RA1的分离鉴定、遗传进化分析及致病性试验[J]. 微生物学通报, 2024, 51(7): 2576-2585. LIN ZM, LIN BB, XIE BL, XU YJ, LIN FQ, YAN L, LI CT, ZHOU HO, LI ZL. Isolation, identification, genetic evolution analysis, and pathogenicity test of Riemerella anatipestifer PT-RA1[J]. Microbiology China, 2024, 51(7): 2576-2585(in Chinese).
    [14] 王静, 周媛媛, 张学谅, 陈欣, 原婧, 尹荣兰, 李睿, 黄晨, 尹荣焕. 副猪嗜血杆菌疫苗研究进展[J]. 动物医学进展, 2020, 41(3): 92-96. WANG J, ZHOU YY, ZHANG XL, CHEN X, YUAN J, YIN RL, LI R, HUANG C, YIN RH. Progress on Haemophilus parasuis vaccines[J]. Progress in Veterinary Medicine, 2020, 41(3): 92-96(in Chinese).
    [15] 刘元杰, 王秀丽, 李建, 辛凌翔, 朱良全, 张一帜, 姚文生, 刘燕. 副猪嗜血杆菌4型灭活疫苗攻毒菌株的筛选[J]. 中国兽药杂志, 2024, 58(1): 6-12. LIU YJ, WANG XL, LI J, XIN LX, ZHU LQ, ZHANG YZ, YAO WS, LIU Y. Screening of hemophilus parasuis serotype 4 strain[J]. Chinese Journal of Veterinary Drug, 2024, 58(1): 6-12(in Chinese).
    [16] 张一帜, 张媛, 李建, 王秀丽, 刘元杰, 任小侠, 辛凌翔, 宋佳诚, 罗玉峰. 猪胸膜肺炎杆菌免疫机制研究进展[J]. 中国兽医杂志, 2023, 59(4): 80-84. ZHANG YZ, ZHANG Y, LI J, WANG XL, LIU YJ, REN XX, XIN LX, SONG JC, LUO YF. Research progress on immune mechanism of Actinobacillus pleuropneumoniae[J]. Chinese Journal of Veterinary Medicine, 2023, 59(4): 80-84(in Chinese).
    [17] LOERA-MURO A, ANGULO C. New trends in innovative vaccine development against Actinobacillus pleuropneumoniae[J]. Veterinary Microbiology, 2018, 217: 66-75.
    [18] SOTO PEREZCHICA MM, GUERRERO BARRERA AL, AVELAR GONZALEZ FJ, TRISTAN TQ, MARIN OM. Actinobacillus pleuropneumoniae, surface proteins and virulence: a review[J]. Frontiers in Veterinary Science, 2023, 10: 1276712.
    [19] 于海涛, 孟信淳, 陈玉霞. 猪肺炎支原体流行病学及防控研究进展[J]. 中国动物检疫, 2021, 38(10): 83-86, 131. YU HT, MENG XC, CHEN YX. Research progress on epidemiology and control of Mycoplasma hyopneumoniae[J]. China Animal Health Inspection, 2021, 38(10): 83-86, 131(in Chinese).
    [20] 谢倩茹, 陈颖钰, 胡长敏, 郭爱珍. 牛多杀性巴氏杆菌疫苗研究进展[J]. 中国奶牛, 2015(15): 22-27. XIE QR, CHEN YY, HU CM, GUO AZ. Progress on the Vaccine of Pasteurella multocida in Cattle[J]. China Dairy Cattle, 2015(15): 22-27(in Chinese).
    [21] 傅国平. 细菌疫苗的发展历史及研究现状[D]. 重庆: 重庆医科大学硕士学位论文, 2013. FU GP. Development history and research status of bacterial vaccine[D]. Chongqing: Master’s Thesis of Chongqing Medical University, 2013(in Chinese).
    [22] POLLARD AJ, BIJKER EM. A guide to vaccinology: from basic principles to new developments[J]. Nature Reviews Immunology, 2021, 21(2): 83-100.
    [23] Da SILVA AJ, ZANGIROLAMI TC, NOVO-MANSUR MTM, de CAMPOS GIORDANO R, MARTINS EAL. Live bacterial vaccine vectors: an overview[J]. Brazilian Journal of Microbiology, 2015, 45(4): 1117-1129.
    [24] NELDE A, RAMMENSEE HG, WALZ JS. The peptide vaccine of the future[J]. Molecular & Cellular Proteomics, 2021, 20: 100022.
    [25] 李伟杰, 蒋桃珍, 魏财文, 赵耘, 岂晓鑫, 娜琳, 冯忠武. 我国兽用细菌疫苗生产用微生物的惠益分享现状与对策建议[J]. 中国兽药杂志, 2015, 49(11): 1-4. LI WJ, JIANG TZ, WEI CW, ZHAO Y, QI XX, NA L, FENG ZW. The status quo and countermeasures of benefit-sharing of veterinary vaccines production with bacteriain China[J]. Chinese Journal of Veterinary Drug, 2015, 49(11): 1-4(in Chinese).

    [26] 顾江, 曾浩, 邹全明. 创新细菌疫苗的研究进展及挑战[J]. 中国生物制品学杂志, 2021, 34(9): 1017-1022. GU J, ZENG H, ZOU QM. Advances and challenges in research on innovative bacterial vaccines[J]. Chinese Journal of Biologicals, 2021, 34(9): 1017-1022(in Chinese).
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胡云皓,刘燕,朱良全. 我国畜禽细菌类主要兽医病原微生物及其疫苗研制与应用概况[J]. 微生物学通报, 2025, 52(3): 896-904

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  • 收稿日期:2024-06-14
  • 录用日期:2024-08-09
  • 在线发布日期: 2025-03-19
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